- Saab, Elie - Designer based in Beirut, Lebanon. Site includes biography, collections of haute couture, prêt-à-porter, and accessories, locations of shops and showrooms, and a contact form.
- Saenz, Uriel - Designer based in Los Angeles. Site includes collections, press clippings and contact information.
- Sander, Jil - German designer. Site provides contact information.
- Sander, Malou - Danish designer whose line is called "Múus". Site includes background information on the designer and her company, awards, collections, video clips of runway shows, press releases, and contact information. Most of the site is in English, some material in Danish.
- Sapundjievi, Gergana and Maria - Bulgarian sisters, designers of the Adda Couture line. Site includes bios, sketches, ready-to-wear collection, press clippings, and contact information.
- Scarlett, Austin - New York designer, originally from Oregon, best known as one of the contestants on the television program Project Runway. Site includes bio, collections, press clippings and email contact link.
- Schkrew - Designers of "bootlets" -- also known as shoe covers or leg warmers, designed to mix and match with shoes to create various bootlike looks. Site includes collections, online shopping, and contact information for retailers and customers interested in custom designs.
- Schnoor, Sophie - Danish designer. Site includes bio, company background, collections, and contact information. Opens full-screen.
- Schouler, Proenza - Designer's site includes stocklist information, collections and contact info.
- SEYES - The design house of Stéphane Martin and Hervé Guétin, who design and manufacture knitwear using only 100% organic, fair-traded materials. Site includes collection, online shopping, company philosophy and creative process, information for press, and area for registered clients. In French.
- Shadé, Kami - Designer based in Toluca Lake, California. Site includes bio, event information and pictures, online shopping, collections and contact information.
- Shahid, Nilofer - Pakistani designer and director of the Meeras fashion house. Site includes bio, collections, press clippings, and contact information.
- Shimada, Junko - Paris-based designer. Collections, store locations, and contact information.
- Shokrian, Jasmin - Site includes collections (photos and videos), bio, store locations and contact information.
- Sigurd, Steinunn - Icelandic designer who has worked for Ralph Lauren, Calvin Klein, Gucci, and La Perla, and now designs her own "STEiNUUN" line. Site includes CV, collections, press clippings, location of Reykjavik store and contact information for Iceland, UK, and US.
- Silva, Ximena - Designer based in Bogota, Colombia. Site includes contact information, video of collection and personal messages from the designer. In Spanish, French, German and English.
- Simmons, Kimora Lee - See Baby Phat.
- Slama, Amir - See Rosa Chá.
- Sleazy Studio - Sofia, Bulgaria based designers and makers of leather garments and accessories for men, women and children, including custom-made articles. Site includes company history, press clippings, collections, materials used, shop and factory locations, and contact information. Site in Bulgarian and English.
- Small, Geoffrey B. - Designer and founder of the Association Internationale des Createurs Independants (an organization for independent designers), originally from Boston and now based in Cavarzere, Italy. Site includes collections, extensive background information, store locations, mission statement and contact information.
- Smith, Paul - British designer's site includes history, collections, fragrances, furniture, china, information on bespoke (custom) design work, advertising, new items, shop locations (including online) and contact information.
- Som, Peter - New York based designer, originally from San Francisco, who has worked for Bill Blass, Michael Kors, and Calvin Klein. Site includes bio, store locations and contact information.
- Sorbier, Franck - French couture designer's site features collections, bio and contact information. In French and English, opens full-screen.
- Steffee, Shelly - Womenswear designer based in New York. Site includes collections, bio, accessories, info on her boutique in New York's Meat Packing District, and contact information.
- Stehlik, Anja - Croatian designer's site includes bio, influences, list of shops where her designs are available and contact information.
- Strelli, Olivier - Designer of Italian descent, born in Congo, based in Belgium. History, collections, press area, locations of showrooms, shops, and exhibitions. Site in English, French and Dutch.
- Sugarlime - Designer, manufacturer, importer and retailer of earrings, necklaces, bracelets and accessories.
- Sui, Anna - Official site of American fashion designer Anna Sui, featuring her personal/career history, sales of her cosmetics, fragrance and accessory lines, beauty tips, and images from her shows.
- Sylvester, Kate - New Zealand designer's site features bio, press, collections, store locations and contact information.